l-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

Newborn piglets develop pulmonary hypertension and have diminished pulmonary vascular nitric oxide (NO) production when exposed to chronic hypoxia. NO is produced by endothelial NO synthase (eNOS) in the pulmonary vascular endothelium using l-arginine as a substrate and producing l-citrulline as a b...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Ananthakrishnan, Madhumita, Barr, Frederick E., Summar, Marshall L., Smith, Heidi A., Kaplowitz, Mark, Cunningham, Gary, Magarik, Jordan, Zhang, Yongmei, Fike, Candice D.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132308/
https://ncbi.nlm.nih.gov/pubmed/19617312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00017.2009
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