l-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

Newborn piglets develop pulmonary hypertension and have diminished pulmonary vascular nitric oxide (NO) production when exposed to chronic hypoxia. NO is produced by endothelial NO synthase (eNOS) in the pulmonary vascular endothelium using l-arginine as a substrate and producing l-citrulline as a b...

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Publié dans:Am J Physiol Lung Cell Mol Physiol
Auteurs principaux: Ananthakrishnan, Madhumita, Barr, Frederick E., Summar, Marshall L., Smith, Heidi A., Kaplowitz, Mark, Cunningham, Gary, Magarik, Jordan, Zhang, Yongmei, Fike, Candice D.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132308/
https://ncbi.nlm.nih.gov/pubmed/19617312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00017.2009
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