Prolonged hypoxia augments l-citrulline transport by System A in the newborn piglet pulmonary circulation

AIMS: Pulmonary arterial endothelial cells (PAECs) express the enzymes needed for generation of l-arginine from intracellular l-citrulline but do not express the enzymes needed for de novo l-citrulline synthesis. Hence, l-citrulline levels in PAECs are dependent on l-citrulline transport. Once gener...

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Detalhes bibliográficos
Main Authors: Fike, Candice D., Sidoryk-Wegrzynowicz, Marta, Aschner, Michael, Summar, Marshall, Prince, Lawrence S., Cunningham, Gary, Kaplowitz, Mark, Zhang, Yongmei, Aschner, Judy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400357/
https://ncbi.nlm.nih.gov/pubmed/22673370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs186
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