ARID1A alterations and their clinical significance in cholangiocarcinoma

BACKGROUND: ARID1A is a member of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor and several therapeutic targets in ARID1A-mutated cancers are currently under development, including EZH2. A synthetic lethal relationship between ARID1A and EZH2 has been revealed in sever...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Namjan, Achira, Techasen, Anchalee, Loilome, Watcharin, Sa-ngaimwibool, Prakasit, Jusakul, Apinya
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719290/
https://ncbi.nlm.nih.gov/pubmed/33344089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10464
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