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ARID1A alterations and their clinical significance in cholangiocarcinoma

BACKGROUND: ARID1A is a member of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor and several therapeutic targets in ARID1A-mutated cancers are currently under development, including EZH2. A synthetic lethal relationship between ARID1A and EZH2 has been revealed in sever...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PeerJ
Main Authors: Namjan, Achira, Techasen, Anchalee, Loilome, Watcharin, Sa-ngaimwibool, Prakasit, Jusakul, Apinya
פורמט: Artigo
שפה:Inglês
יצא לאור: PeerJ Inc. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719290/
https://ncbi.nlm.nih.gov/pubmed/33344089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10464
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