Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway

Progranulin (PGRN) is a growth factor normally expressed in rapidly cycling epithelial cells for growth, differentiation, and motility. Several studies have shown the association of PGRN overexpression with the progression of numerous malignancies, including cholangiocarcinoma (CCA). However, the un...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Daya, Minerva, Loilome, Watcharin, Techasen, Anchalee, Thanee, Malinee, Sa-Ngiamwibool, Prakasit, Titapun, Attapol, Yongvanit, Puangrat, Namwat, Nisana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783154/
https://ncbi.nlm.nih.gov/pubmed/29403285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155511
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