Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway

Progranulin (PGRN) is a growth factor normally expressed in rapidly cycling epithelial cells for growth, differentiation, and motility. Several studies have shown the association of PGRN overexpression with the progression of numerous malignancies, including cholangiocarcinoma (CCA). However, the un...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Daya, Minerva, Loilome, Watcharin, Techasen, Anchalee, Thanee, Malinee, Sa-Ngiamwibool, Prakasit, Titapun, Attapol, Yongvanit, Puangrat, Namwat, Nisana
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783154/
https://ncbi.nlm.nih.gov/pubmed/29403285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155511
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