Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway

Progranulin (PGRN) is a growth factor normally expressed in rapidly cycling epithelial cells for growth, differentiation, and motility. Several studies have shown the association of PGRN overexpression with the progression of numerous malignancies, including cholangiocarcinoma (CCA). However, the un...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Daya, Minerva, Loilome, Watcharin, Techasen, Anchalee, Thanee, Malinee, Sa-Ngiamwibool, Prakasit, Titapun, Attapol, Yongvanit, Puangrat, Namwat, Nisana
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783154/
https://ncbi.nlm.nih.gov/pubmed/29403285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155511
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