Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway

Progranulin (PGRN) is a growth factor normally expressed in rapidly cycling epithelial cells for growth, differentiation, and motility. Several studies have shown the association of PGRN overexpression with the progression of numerous malignancies, including cholangiocarcinoma (CCA). However, the un...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Autores principales: Daya, Minerva, Loilome, Watcharin, Techasen, Anchalee, Thanee, Malinee, Sa-Ngiamwibool, Prakasit, Titapun, Attapol, Yongvanit, Puangrat, Namwat, Nisana
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783154/
https://ncbi.nlm.nih.gov/pubmed/29403285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S155511
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