CD44 variant‐dependent redox status regulation in liver fluke‐associated cholangiocarcinoma: A target for cholangiocarcinoma treatment

Expression of CD44, especially the variant isoforms (CD44v) of this major cancer stem cell marker, contributes to reactive oxygen species (ROS) defense through stabilizing xCT (a cystine–glutamate transporter) and promoting glutathione synthesis. This enhances cancer development and increases chemot...

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Publicat a:Cancer Sci
Autors principals: Thanee, Malinee, Loilome, Watcharin, Techasen, Anchalee, Sugihara, Eiji, Okazaki, Shogo, Abe, Shinya, Ueda, Shiho, Masuko, Takashi, Namwat, Nisana, Khuntikeo, Narong, Titapun, Attapol, Pairojkul, Chawalit, Saya, Hideyuki, Yongvanit, Puangrat
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946726/
https://ncbi.nlm.nih.gov/pubmed/27176078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12967
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