Suppression of 14-3-3ζ in cholangiocarcinoma cells inhibits proliferation through attenuated Akt activity, enhancing chemosensitivity to gemcitabine

The protein 14-3-3ζ contributes important regulatory functions in several cellular processes via binding to phosphorylated serine/threonine residues, which promotes cell cycle progression, cell proliferation and anti-apoptosis in multiple types of cancer. The aim of the present study was to investig...

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Udgivet i:Oncol Lett
Main Authors: Kittirat, Yingpinyapat, Techasen, Anchalee, Thongchot, Suyanee, Loilome, Watcharin, Thanan, Raynoo, Yongvanit, Puangrat, Sungkhamanon, Sakkarn, Titapun, Attapol, Khuntikeo, Narong, Namwat, Nisana
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768060/
https://ncbi.nlm.nih.gov/pubmed/29387222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7326
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