DNA methyltransferase 3B plays a protective role against hepatocarcinogenesis caused by chronic inflammation via maintaining mitochondrial homeostasis

Most hepatocellular carcinomas (HCCs) develop on the basis of chronic hepatitis, but the mechanism of epigenetic regulation in inflammatory hepatocarcinogenesis has yet to be elucidated. Among de novo DNA methyltransferases (DNMTs), DNMT3B has lately been reported to act specifically on actively tra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Iguchi, Eriko, Takai, Atsushi, Takeda, Haruhiko, Kumagai, Ken, Arasawa, Soichi, Eso, Yuji, Shimizu, Takahiro, Ueda, Yoshihide, Marusawa, Hiroyuki, Seno, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719166/
https://ncbi.nlm.nih.gov/pubmed/33277576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78151-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados