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Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation

The linkage, length, and architecture of ubiquitin (Ub) chains are all important variables in providing tight control over many biological paradigms. There are clear roles for branched architectures in regulating proteasome-mediated degradation, however the proteins that selectively recognize and pr...

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Publicat a:Mol Cell
Autors principals: Deol, Kirandeep K., Crowe, Sean O., Du, Jiale, Bisbee, Heather A., Guenette, Robert G., Strieter, Eric R.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718437/
https://ncbi.nlm.nih.gov/pubmed/33156996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.017
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