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Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation

The linkage, length, and architecture of ubiquitin (Ub) chains are all important variables in providing tight control over many biological paradigms. There are clear roles for branched architectures in regulating proteasome-mediated degradation, however the proteins that selectively recognize and pr...

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Vydáno v:Mol Cell
Hlavní autoři: Deol, Kirandeep K., Crowe, Sean O., Du, Jiale, Bisbee, Heather A., Guenette, Robert G., Strieter, Eric R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718437/
https://ncbi.nlm.nih.gov/pubmed/33156996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.017
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