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A Fluorescence Polarization-Based Competition Assay for Measuring Interactions between Unlabeled Ubiquitin Chains and UCH37•RPN13

Ubiquitin chains regulate distinct signaling events through cooperative interactions with effector proteins and deubiquitinases. Measuring the strength of these interactions is often challenging; either large amounts of material are required or one of the binding partners must be labeled for detecti...

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Detalles Bibliográficos
Publicado en:Anal Biochem
Main Authors: Du, Jiale, Strieter, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976553/
https://ncbi.nlm.nih.gov/pubmed/29698671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2018.04.018
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