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Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo

Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles of ubiquitin chains, however, is difficult due to their complex chain topologies. Branched ubiquitin chains are particularly challenging, as...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Crowe, Sean O., Rana, Ambar S. J. B., Deol, Kirandeep K., Ge, Ying, Strieter, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541364/
https://ncbi.nlm.nih.gov/pubmed/28291339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03675
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