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Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo

Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles of ubiquitin chains, however, is difficult due to their complex chain topologies. Branched ubiquitin chains are particularly challenging, as...

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Veröffentlicht in:Anal Chem
Hauptverfasser: Crowe, Sean O., Rana, Ambar S. J. B., Deol, Kirandeep K., Ge, Ying, Strieter, Eric R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541364/
https://ncbi.nlm.nih.gov/pubmed/28291339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03675
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