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Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo

Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles of ubiquitin chains, however, is difficult due to their complex chain topologies. Branched ubiquitin chains are particularly challenging, as...

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Détails bibliographiques
Publié dans:Anal Chem
Auteurs principaux: Crowe, Sean O., Rana, Ambar S. J. B., Deol, Kirandeep K., Ge, Ying, Strieter, Eric R.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541364/
https://ncbi.nlm.nih.gov/pubmed/28291339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b03675
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