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Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains

[Image: see text] Protein ubiquitylation, one of the most prevalent post-translational modifications in eukaryotes, is involved in regulating nearly every cellular signaling pathway. The vast functional range of ubiquitylation has largely been attributed to the formation of a diverse array of polyme...

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Pubblicato in:Biochemistry
Autori principali: Valkevich, Ellen M., Sanchez, Nicholas A., Ge, Ying, Strieter, Eric R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372068/
https://ncbi.nlm.nih.gov/pubmed/25023374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5006305
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