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Characterization of Polyubiquitin Chain Structure by Middle-down Mass Spectrometry
Ubiquitin (Ub) is a 76 amino acid polypeptide that modifies a wide range of proteins in the types of monomer or polymers, and functional consequence of ubiquitination is modulated by the length and topologies of polyUb chains. Whereas polyUb chains are usually analyzed by fully trypsin digestion and...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663523/ https://ncbi.nlm.nih.gov/pubmed/18351785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac800016w |
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