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Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer

Chemoprevention trials for prostate cancer (PCa) by androgen receptor or androgen synthesis inhibition have proven ineffective. Recently, it has been demonstrated that the histone methlytransferase, EZH2 is de-regulated in mouse and human high-grade prostatic intraepithelial neoplasia (HG-PIN). Usin...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Prev Res (Phila)
Päätekijät: Burkhart, Deborah L., Morel, Katherine L., Wadosky, Kristine M., Labbé, David P., Galbo, Phillip M., Dalimov, Zafardjan, Xu, Bo, Loda, Massimo, Ellis, Leigh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718322/
https://ncbi.nlm.nih.gov/pubmed/32917647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0186
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