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Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer

Chemoprevention trials for prostate cancer (PCa) by androgen receptor or androgen synthesis inhibition have proven ineffective. Recently, it has been demonstrated that the histone methlytransferase, EZH2 is de-regulated in mouse and human high-grade prostatic intraepithelial neoplasia (HG-PIN). Usin...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Burkhart, Deborah L., Morel, Katherine L., Wadosky, Kristine M., Labbé, David P., Galbo, Phillip M., Dalimov, Zafardjan, Xu, Bo, Loda, Massimo, Ellis, Leigh
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718322/
https://ncbi.nlm.nih.gov/pubmed/32917647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0186
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