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A Fresh Approach to Targeting Aging Cells: CAR-T Cells Enhance Senolytic Specificity
Senescence is a critical factor in several diseases, yet senolytic therapies targeting senescent cells remain hindered by lack of specificity. In the June issue of Nature, Amor et al. (2020) develop chimeric antigen receptor (CAR)-T cells targeting uPAR, a novel senescent-cell marker, to treat liver...
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| 出版年: | Cell Stem Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7717659/ https://ncbi.nlm.nih.gov/pubmed/32763179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.07.010 |
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