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A Fresh Approach to Targeting Aging Cells: CAR-T Cells Enhance Senolytic Specificity
Senescence is a critical factor in several diseases, yet senolytic therapies targeting senescent cells remain hindered by lack of specificity. In the June issue of Nature, Amor et al. (2020) develop chimeric antigen receptor (CAR)-T cells targeting uPAR, a novel senescent-cell marker, to treat liver...
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| Pubblicato in: | Cell Stem Cell |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7717659/ https://ncbi.nlm.nih.gov/pubmed/32763179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.07.010 |
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