DIPG-08. ELECTRONIC SEQUENCING PROVIDES OPTIMIZED QUANTIFICATION OF SERIAL, MULTI-GENE MOLECULAR RESPONSE IN THE CSF OF CHILDREN WITH HIGH-GRADE GLIOMA

BACKGROUND: For pediatric high-grade glioma (pHGG), non-invasive methods for diagnosis and surveillance are needed. Tumors release DNA (tDNA) into cerebrospinal fluid (CSF), allowing for detection of tumor-associated mutations by CSF sampling. We hypothesized that direct, electronic analysis of tDNA...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bruzek, Amy, Muruganand, Ashwath, Ravi, Karthik, Wadden, Jack, Babila, Clarissa, Tunkle, Leo, Wierzbicki, Kyle, Stallard, Stefanie, Cantor, Evan, Qin, Tingting, Wolfe, Ian, Mody, Rajen, Muraszko, Karin, Franson, Andrea, Robertson, Patrica, Maher, Cormac, Garton, Hugh, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Diffuse Midline Glioma/DIPG
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715796/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.059
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