PDTM-10. USE OF A NOVEL, HAND-HELD, ELECTRONIC DNA ANALYSIS PLATFORM TO QUANTIFY MULTI-GENE MOLECULAR RESPONSE IN CSF OF PATIENTS WITH HIGH-GRADE GLIOMA

BACKGROUND: For midline tumors, surgical biopsy risks neurological injury. Non-invasive methods for diagnosis and surveillance are greatly needed. Tumors release DNA into cerebrospinal fluid (CSF-ctDNA), allowing for potential detection and serial monitoring of tumor-associated genetic mutations by...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Bruzek, Amy, Tunkle, Leo, Babila, Clarissa, Muruganand, Ashwath, Stallard, Stefanie, Thamilselvan, Veena, Qin, Tingting, Wolfe, Ian, Mody, Rajen, Robertson, Patricia, Maher, Cormac, Muraszko, Karin, Garton, Hugh, Koschmann, Carl
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Pediatric Tumors
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847908/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.786
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