PDTM-29. CSF H3F3A K27M CIRCULATING TUMOR DNA COPY NUMBER QUANTIFIES TUMOR GROWTH AND TREATMENT RESPONSE

Primary brain tumors and CNS metastases shed circulating tumor DNA (ctDNA) into the CSF, which can be assessed for tumor-associated mutations. Thus far, there have been no extensive studies using droplet digital PCR (ddPCR) to detect and quantify ctDNA in the CSF of pediatric high-grade brain tumor...

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Publicat a:Neuro Oncol
Autors principals: Stallard, Stefanie, G. Savelieff, Masha, Mullan, Brendan, Miklja, Zachary, Bruzek, Amy, Garcia, Taylor, Wierzbicki, Kyle, Singer, Benjamin, Hashizume, Rintaro, Montero Carcaboso, Angel, Q. McMurray, Kaitlin, Heth, Jason, Muraszko, Karin, L. Robertson, Patricia, Mody, Rajen, Venneti, Sriram, Garton, Hugh, Koschmann, Carl
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217671/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.870
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