MODL-19. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL UP- OR DOWN-STREAM INHIBITION

The survival of children with DIPG remains dismal, with new treatments desperately needed. In the era of precision medicine, targeted therapies represent an exciting treatment opportunity, yet resistance can rapidly emerge, playing an important role in treatment failure. In a prospective biopsy-stra...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Depani, Sarita, O’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Preclinical Models/Experimental Therapy/Drug Discovery
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715767/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.592
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia