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TBIO-06. BDNF-TRKB SIGNALING REGULATES NEURON-GLIOMA SYNAPTOGENESIS AND PROMOTES TUMOR PROGRESSION

Pediatric high-grade gliomas (pHGG) are a devastating group of diseases that urgently require novel therapeutic options. We have previously demonstrated that pHGGs hijack mechanisms of brain development and plasticity to their advantage. Here, we investigated the role of microenvironmental BDNF on p...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Taylor, Kathryn, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.834
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