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TBIO-06. BDNF-TRKB SIGNALING REGULATES NEURON-GLIOMA SYNAPTOGENESIS AND PROMOTES TUMOR PROGRESSION

Pediatric high-grade gliomas (pHGG) are a devastating group of diseases that urgently require novel therapeutic options. We have previously demonstrated that pHGGs hijack mechanisms of brain development and plasticity to their advantage. Here, we investigated the role of microenvironmental BDNF on p...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Taylor, Kathryn, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715419/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.834
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