An active role for neurons in glioma progression: making sense of Scherer’s structures

door Gillespie, Shawn, Monje, Michelle
Gepubliceerd in Neuro Oncol (2018)

DIPG-48. DIFFUSE INTRINSIC PONTINE GLIOMA CELLS ARE INTERCONNECTED BY ‘TUMOR MICROTUBES’

door Gillespie, Shawn, Nagaraja, Surya, Monje-Deisseroth, Michelle
Gepubliceerd in Neuro Oncol (2018)

PDTM-21. MULTI-MODAL PROFILING OF PEDIATRIC HIGH-GRADE GLIOMA SINGLE CELLS USING PATCH-SEQ

door Gillespie, Shawn, Arzt, Marlene, Woo, Pamelyn, Monje, Michelle
Gepubliceerd in Neuro Oncol (2019)

TBIO-06. BDNF-TRKB SIGNALING REGULATES NEURON-GLIOMA SYNAPTOGENESIS AND PROMOTES TUMOR PROGRESSION

door Taylor, Kathryn, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Gepubliceerd in Neuro Oncol (2020)

HGG-05. NEURONAL ACTIVITY PROMOTES PEDIATRIC HIGH-GRADE GLIOMA GROWTH THROUGH A NLGN3-CSPG4 SIGNALING AXIS

door Gillespie, Shawn, Kim, Yoon, Geraghty, Anna, Woo, Pamelyn, Monje, Michelle
Gepubliceerd in Neuro Oncol (2021)

HGG-21. MALIGNANT SYNAPTIC PLASTICITY IN PEDIATRIC HIGH-GRADE GLIOMAS

door Taylor, Kathryn, Barron, Tara, Hartmann, Griffin, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Gepubliceerd in Neuro Oncol (2021)

DIPG-52. ACTIVE CHROMATIN IN H3K27M DIPG REVEALS DISTINCT EPIGENETIC SUBTYPES AND SUBTYPE-SPECIFIC MECHANISMS OF PATHOGENESIS

door Nagaraja, Surya, Quezada, Michael, Gillespie, Shawn, Geraghty, Anna, Hovestadt, Volker, Filbin, Mariella, Suva, Mario, Nazarian, Javad, Monje, Michelle
Gepubliceerd in Neuro Oncol (2018)

Insulator dysfunction and oncogene activation in IDH mutant gliomas

door Flavahan, William A., Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Venteicher, Andrew S., Stemmer-Rachamimov, Anat O., Suvà, Mario L., Bernstein, Bradley E.
Gepubliceerd in Nature (2015)

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq

door Karaayvaz, Mihriban, Cristea, Simona, Gillespie, Shawn M., Patel, Anoop P., Mylvaganam, Ravindra, Luo, Christina C., Specht, Michelle C., Bernstein, Bradley E., Michor, Franziska, Ellisen, Leif W.
Gepubliceerd in Nat Commun (2018)

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

door Venkatesh, Humsa S., Tam, Lydia T., Woo, Pamelyn J., Lennon, James, Nagaraja, Surya, Gillespie, Shawn M., Ni, Jing, Duveau, Damien Y., Morris, Patrick J., Zhao, Jean J., Thomas, Craig J., Monje, Michelle
Gepubliceerd in Nature (2017)

DIPG-21. ELECTRICAL INTEGRATION OF GLIOMA INTO NEURAL CIRCUITRY

door Venkatesh, Humsa, Morishita, Wade, Geraghty, Anna, Silverbush, Dana, Arzt, Marlene, Tam, Lydia, Ponnuswami, Anitha, Gillespie, Shawn, Agarwal, Amit, Regev, Aviv, Vogel, Hannes, Bergles, Dwight, Suva, Mario, Malenka, Robert, Monje, Michelle
Gepubliceerd in Neuro Oncol (2019)

Histone variant and cell context determine H3K27M reprogramming of the enhancer landscape and oncogenic state

door Nagaraja, Surya, Quezada, Michael A., Gillespie, Shawn M., Arzt, Marlene, Lennon, James J., Woo, Pamelyn J., Hovestadt, Volker, Kambhampati, Madhuri, Filbin, Mariella G., Suva, Mario L., Nazarian, Javad, Monje, Michelle
Gepubliceerd in Mol Cell (2019)

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma

door Ryan, Russell J.H., Drier, Yotam, Whitton, Holly, Cotton, M. Joel, Kaur, Jasleen, Issner, Robbyn, Gillespie, Shawn, Epstein, Charles B., Nardi, Valentina, Sohani, Aliyah R., Hochberg, Ephraim P., Bernstein, Bradley E.
Gepubliceerd in Cancer Discov (2015)

An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma

door Rheinbay, Esther, Suvà, Mario L., Gillespie, Shawn M., Wakimoto, Hiroaki, Patel, Anoop P., Shahid, Mohammad, Oksuz, Ozgur, Rabkin, Samuel D., Martuza, Robert L., Rivera, Miguel N., Louis, David N., Kasif, Simon, Chi, Andrew S., Bernstein, Bradley E.
Gepubliceerd in 2013

A multiplexed system for quantitative comparisons of chromatin landscapes

door van Galen, Peter, Viny, Aaron D., Ram, Oren, Ryan, Russell J.H., Cotton, Matthew J., Donohue, Laura, Sievers, Cem, Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Carroll, Kaitlin M., Cross, Michael B., Levine, Ross L., Bernstein, Bradley E.
Gepubliceerd in Mol Cell (2015)

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

door Patel, Anoop P., Tirosh, Itay, Trombetta, John J., Shalek, Alex K., Gillespie, Shawn M., Wakimoto, Hiroaki, Cahill, Daniel P., Nahed, Brian V., Curry, William T., Martuza, Robert L., Louis, David N., Rozenblatt-Rosen, Orit, Suvà, Mario L., Regev, Aviv, Bernstein, Bradley E.
Gepubliceerd in 2014

TMIC-18. ELECTRICAL CIRCUIT INTEGRATION OF GLIOMA THROUGH NEURON-GLIOMA SYNAPSES AND POTASSIUM CURRENTS

door Venkatesh, Humsa, Morishita, Wade, Geraghty, Anna, Silverbush, Dana, Gillespie, Shawn, Arzt, Marlene, Tam, Lydia, Ponnuswami, Anitha, Ni, Lijun, Woo, Pamelyn, Taylor, Kathryn, Agarwal, Amit, Regev, Aviv, Brang, David, Vogel, Hannes, Hervey-Jumper, Shawn, Bergles, Dwight, Suvà, Mario, Malenka, Robert, Monje, Michelle
Gepubliceerd in Neuro Oncol (2019)

Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer

door Puram, Sidharth V., Tirosh, Itay, Parikh, Anuraag S., Patel, Anoop P., Yizhak, Keren, Gillespie, Shawn, Rodman, Christopher, Luo, Christina L., Mroz, Edmund A., Emerick, Kevin S., Deschler, Daniel G., Varvares, Mark A., Mylvaganam, Ravi, Rozenblatt-Rosen, Orit, Rocco, James W., Faquin, William C., Lin, Derrick T., Regev, Aviv, Bernstein, Bradley E.
Gepubliceerd in Cell (2017)

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation

door Wang, Xiaofeng, Lee, Ryan S., Alver, Burak H., Haswell, Jeffrey R., Wang, Su, Mieczkowski, Jakub, Drier, Yotam, Gillespie, Shawn M., Archer, Tenley C., Wu, Jennifer N., Tzvetkov, Evgeni P., Troisi, Emma C., Pomeroy, Scott L., Biegel, Jaclyn A., Tolstorukov, Michael Y., Bernstein, Bradley E., Park, Peter J., Roberts, Charles W. M.
Gepubliceerd in Nat Genet (2016)

Electrical and synaptic integration of glioma into neural circuits

door Venkatesh, Humsa S., Morishita, Wade, Geraghty, Anna C., Silverbush, Dana, Gillespie, Shawn M., Arzt, Marlene, Tam, Lydia T., Espenel, Cedric, Ponnuswami, Anitha, Ni, Lijun, Woo, Pamelyn J., Taylor, Kathryn R., Agarwal, Amit, Regev, Aviv, Brang, David, Vogel, Hannes, Hervey-Jumper, Shawn, Bergles, Dwight E., Suvà, Mario L., Malenka, Robert C., Monje, Michelle
Gepubliceerd in Nature (2019)