DIPG-10. OPTIMAL HDAC INHIBITION IN DIFFUSE INTRINSIC PONTINE GLIOMA

As the majority of diffuse intrinsic pontine glioma (DIPG) have H3K27M mutations, epigenetic-targeting agents have been studied, though evaluations have been limited by their model systems, untranslatable drug concentrations, and/or evasive mechanisms of action. To develop a more translational model...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Vitanza, Nicholas, Biery, Matt, Myers, Carrie, Ferguson, Eric, Park, Giulia, Noll, Alyssa, Pakiam, Fiona, Girard, Emily, Morris, Shelli, Cole, Bonnie, Brusniak, Mi-Youn, Mhyre, Andrew, Olson, James
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Diffuse Midline Glioma/DIPG
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715293/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.060
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