DDEL-04. ENGINEERED NANOCARRIERS TO ENHANCE DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER

Pediatric central nervous system tumors are the leading cause of cancer death in children. Promising therapeutics have been identified, but the ability to deliver an effective concentration to the tumor without causing excessive systemic toxicity remains a challenge. To address this, we leveraged a...

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Publicat a:Neuro Oncol
Autors principals: Straehla, Joelle P, Hajal, Cynthia, Safford, Hannah, Offeddu, Giovanni, Wyckoff, Jeffrey, Kamm, Roger D, Hammond, Paula T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Drug Delivery/Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715230/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.039
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