DDEL-15. NANOTHERAPEUTIC TARGETING OF TUMOR ENDOTHELIUM FOR ENHANCING DRUG DELIVERY PAST THE BLOOD-BRAIN BARRIER

OBJECTIVE: The Sonic Hedgehog (SHH) medulloblastoma subgroup accounts for ~25% of all cases and has an intermediate prognosis. Current therapies result in devastating morbidities including intellectual disability and secondary malignancies. Although molecularly targeted agents against the SHH pathwa...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kiguchi, Hiro, Tylawsky, Daniel, Vaynshteyn, Jake, Gerwin, Jeffrey, Manzari, Mandana, Shah, Janki, Li, Na, Shamay, Yosi, Greenblatt, Matthew, Heller, Daniel, Raju, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Drug Delivery/Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715705/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.050
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