SCIDOT-41. NANOTHERAPEUTIC TARGETING OF TUMOR ENDOTHELIUM FOR ENHANCING DRUG DELIVERY PAST THE BLOOD-BRAIN BARRIER

OBJECTIVE: The Sonic Hedgehog (SHH) medulloblastoma subgroup accounts for ~25% of all cases and has an intermediate prognosis. Current conventional therapies result in devastating morbidities including intellectual disability and secondary malignancies. Although molecularly targeted agents that inhi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kiguchi, Hiroto, Manzari, Mandana, Vaynshteyn, Jake, Gerwin, Jeffrey, Tylawsky, Daniel, Li, Na, Shah, Janki, Shamay, Yosi, Greenblatt, Matthew, Heller, Daniel, Praveen Raju, G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846632/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1177
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