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P-selectin is a nanotherapeutic delivery target in the tumor microenvironment
Disseminated tumors are poorly accessible to nanoscale drug delivery systems because of the vascular barrier, which attenuates extravasation at the tumor site. We investigated P-selectin, a molecule expressed on activated vasculature that facilitates metastasis by arresting tumor cells at the endoth...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064151/ https://ncbi.nlm.nih.gov/pubmed/27358497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf7374 |
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