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THER-15. FUNCTIONALIZED NANOPARTICLE TRAFFICKING ASSESSED IN A NOVEL MICROFLUIDIC MODEL OF THE BLOOD-BRAIN BARRIER WITH HIGH GRADE GLIOMA SPHEROIDS

High grade gliomas (HGG) are the most common malignant brain tumor in children, and remain effectively incurable with 5 year overall survival. We developed a library of functionalized nanoparticles (NPs) with ligands targeting BBB shuttle mechanisms. Using the layer-by-layer (LbL) platform to functi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Straehla, Joelle P, Hajal, Cynthia, Dacoba, Tamara, Kamm, Roger D, Hammond, Paula T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477194/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.222
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