ATRT-19. EPIGENETIC REPROGRAMMING LEADS TO INNATE IMMUNE PATHWAY ACTIVATION IN AT/RT

BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive brain tumors affecting early childhood and are characterized by bi-allelic inactivation of the SMARCB1 gene. Though patients benefit from multimodal therapy, there is no improvement in overall survival necessitating explorat...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Hariharan, Seethalakshmi, Kilic, Cem, Bowie, Michelle, Reitman, Zachary, Ashley, David
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Atypical Teratoid/Rhabdoid Tumors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715210/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.018
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