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Methylthioadenosine (MTA) boosts cell‐specific productivities of Chinese hamster ovary cultures: dosage effects on proliferation, cell cycle and gene expression

A major goal for process and cell engineering in the biopharmaceutical industry is enhancing production through increasing volumetric and cell‐specific productivities (CSP). Here, we present 5′‐deoxy‐5′‐(methylthio)adenosine (MTA), the degradation product of S‐(5′‐adenosyl)‐L‐methionine (SAM), as a...

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Bibliografische gegevens
Gepubliceerd in:FEBS Open Bio
Hoofdauteurs: Verhagen, Natascha, Zieringer, Julia, Takors, Ralf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714083/
https://ncbi.nlm.nih.gov/pubmed/33128321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13019
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