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Methylthioadenosine (MTA) boosts cell‐specific productivities of Chinese hamster ovary cultures: dosage effects on proliferation, cell cycle and gene expression

A major goal for process and cell engineering in the biopharmaceutical industry is enhancing production through increasing volumetric and cell‐specific productivities (CSP). Here, we present 5′‐deoxy‐5′‐(methylthio)adenosine (MTA), the degradation product of S‐(5′‐adenosyl)‐L‐methionine (SAM), as a...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Verhagen, Natascha, Zieringer, Julia, Takors, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714083/
https://ncbi.nlm.nih.gov/pubmed/33128321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13019
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