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Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents
OBJECTIVES: The discovery and development of TB drugs has met limited success, with two new drugs approved over the last 40 years. Part of the difficulty resides in the lack of well-established in vitro or in vivo targets of potency and physicochemical and pharmacokinetic parameters. In an attempt t...
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| Publicado no: | J Antimicrob Chemother |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7714050/ https://ncbi.nlm.nih.gov/pubmed/25587994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku457 |
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