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Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents

OBJECTIVES: The discovery and development of TB drugs has met limited success, with two new drugs approved over the last 40 years. Part of the difficulty resides in the lack of well-established in vitro or in vivo targets of potency and physicochemical and pharmacokinetic parameters. In an attempt t...

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Detalles Bibliográficos
Publicado en:J Antimicrob Chemother
Main Authors: Lakshminarayana, Suresh B., Huat, Tan Bee, Ho, Paul C., Manjunatha, Ujjini H., Dartois, Véronique, Dick, Thomas, Rao, Srinivasa P. S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714050/
https://ncbi.nlm.nih.gov/pubmed/25587994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku457
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