The intracellular lipid-binding domain of human Na(+)/H(+) exchanger 1 forms a lipid-protein co-structure essential for activity

Dynamic interactions of proteins with lipid membranes are essential regulatory events in biology, but remain rudimentarily understood and particularly overlooked in membrane proteins. The ubiquitously expressed membrane protein Na(+)/H(+)-exchanger 1 (NHE1) regulates intracellular pH (pH(i)) with dy...

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Publicado no:Commun Biol
Main Authors: Hendus-Altenburger, Ruth, Vogensen, Jens, Pedersen, Emilie Skotte, Luchini, Alessandra, Araya-Secchi, Raul, Bendsoe, Anne H., Prasad, Nanditha Shyam, Prestel, Andreas, Cardenas, Marité, Pedraz-Cuesta, Elena, Arleth, Lise, Pedersen, Stine F., Kragelund, Birthe B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713384/
https://ncbi.nlm.nih.gov/pubmed/33273619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01455-6
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