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Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer Cells

Prolactin (PRL) and its receptor (PRLR) are implicated in breast cancer invasiveness, although their exact roles remain controversial. The Na(+)/H(+) exchanger (NHE1) plays essential roles in cancer cell motility and invasiveness, but the PRLR and NHE1 have not previously been linked. Here we show t...

詳細記述

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書誌詳細
出版年:Mol Endocrinol
主要な著者: Pedraz-Cuesta, Elena, Fredsted, Jacob, Jensen, Helene H., Bornebusch, Annika, Nejsum, Lene N., Kragelund, Birthe B., Pedersen, Stine F.
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426576/
https://ncbi.nlm.nih.gov/pubmed/27176613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1299
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