Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1

Nef is an accessory protein encoded by human immunodeficiency virus type-1 (HIV-1) and plays important roles in regulating HIV-1 infection and viral replication. Interestingly, HIV-1 Nef can promote degradation of numerous host proteins to disrupt cellular antiviral immune response. However, how HIV...

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Vydáno v:Front Microbiol
Hlavní autoři: Zhang, Hong-Guang, Guo, Jing, Yuan, Yukang, Zuo, Yibo, Liu, Jin, Zhu, Li, Miao, Ying, Chen, Xiangjie, Jin, Lincong, Huang, Fan, Ren, Tengfei, He, Jiuyi, Shi, Weifeng, Wen, Zhenke, Zhu, Chuanwu, Zheng, Hui, Dong, Chunsheng, Qian, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710902/
https://ncbi.nlm.nih.gov/pubmed/33329486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.597972
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