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DeepPheno: Predicting single gene loss-of-function phenotypes using an ontology-aware hierarchical classifier

Predicting the phenotypes resulting from molecular perturbations is one of the key challenges in genetics. Both forward and reverse genetic screen are employed to identify the molecular mechanisms underlying phenotypes and disease, and these resulted in a large number of genotype–phenotype associati...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Kulmanov, Maxat, Hoehndorf, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710064/
https://ncbi.nlm.nih.gov/pubmed/33206638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008453
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