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DeepPheno: Predicting single gene loss-of-function phenotypes using an ontology-aware hierarchical classifier
Predicting the phenotypes resulting from molecular perturbations is one of the key challenges in genetics. Both forward and reverse genetic screen are employed to identify the molecular mechanisms underlying phenotypes and disease, and these resulted in a large number of genotype–phenotype associati...
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| Publicado en: | PLoS Comput Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7710064/ https://ncbi.nlm.nih.gov/pubmed/33206638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008453 |
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