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Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic‐Like Behaviors

STING is known as a central adaptor for sensing cytosolic DNA sensing. Recent studies have provided evidence that STING response is divergent among different cell types. Here, this work demonstrates that STING controls neural progenitor cells (NPCs) by sensing DNA damage in NPCs. The deletion of STI...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Zhang, Dongming, Liu, Chang, Li, Hong, Jiao, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710002/
https://ncbi.nlm.nih.gov/pubmed/33304758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002117
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