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Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic‐Like Behaviors

STING is known as a central adaptor for sensing cytosolic DNA sensing. Recent studies have provided evidence that STING response is divergent among different cell types. Here, this work demonstrates that STING controls neural progenitor cells (NPCs) by sensing DNA damage in NPCs. The deletion of STI...

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Foilsithe in:Adv Sci (Weinh)
Main Authors: Zhang, Dongming, Liu, Chang, Li, Hong, Jiao, Jianwei
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710002/
https://ncbi.nlm.nih.gov/pubmed/33304758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002117
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