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Diversity-Oriented Enzymatic Synthesis of Cyclopropane Building Blocks
While biocatalysis is increasingly incorporated into drug development pipelines, it is less commonly used in the early stages of drug discovery. By engineering a protein to produce a chiral motif with a derivatizable functional handle, biocatalysts can be used to help generate diverse building block...
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| Publicado no: | ACS Catal |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7709968/ https://ncbi.nlm.nih.gov/pubmed/33282460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c01888 |
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