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Diversity-oriented synthesis of peptide-boronic acids by a versatile building-block approach

A new strategy for the synthesis of peptide-boronic acids (PBAs) is presented. 20 Fmoc-protected natural amino acids with orthogonal side-chain protection were straightforwardly converted into their corresponding boron analogues in three simple steps. Subsequent immobilisation on commercially availa...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Hinkes, Stefan P. A., Kämmerer, Severin, Klein, Christian D. P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162117/
https://ncbi.nlm.nih.gov/pubmed/34094250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03999c
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