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3-Cyanoallyl boronates are versatile building blocks in the synthesis of polysubstituted thiophenes

We report the preparation of hitherto unprecedented 3-cyanoallyl boronates using condensation of the parent α-boryl aldehyde and nitriles. The resulting allyl boronates have been used to generate a wide range of borylated thiophenes, which represent a valuable class of heterocycles in modern drug di...

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Vydáno v:Chem Sci
Hlavní autoři: Shao, Wenjie, Kaldas, Sherif J., Yudin, Andrei K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590094/
https://ncbi.nlm.nih.gov/pubmed/28936329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00831g
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