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Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice
The dysregulation of myeloid-derived cell metabolism can drive atherosclerosis. AMP-activated protein kinase (AMPK) controls various aspects of macrophage dynamics and lipid homeostasis, which are important during atherogenesis. Using LysM-Cre to drive the deletion of both the α1 and α2 catalytic su...
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| Veröffentlicht in: | J Lipid Res |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7707174/ https://ncbi.nlm.nih.gov/pubmed/32978273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120001040 |
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