Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice

The dysregulation of myeloid-derived cell metabolism can drive atherosclerosis. AMP-activated protein kinase (AMPK) controls various aspects of macrophage dynamics and lipid homeostasis, which are important during atherogenesis. Using LysM-Cre to drive the deletion of both the α1 and α2 catalytic su...

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Udgivet i:J Lipid Res
Main Authors: LeBlond, Nicholas D., Ghorbani, Peyman, O’Dwyer, Conor, Ambursley, Nia, Nunes, Julia R. C., Smith, Tyler K. T., Trzaskalski, Natasha A., Mulvihill, Erin E., Viollet, Benoit, Foretz, Marc, Fullerton, Morgan D.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707174/
https://ncbi.nlm.nih.gov/pubmed/32978273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120001040
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