Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

BACKGROUND AND PURPOSE: There is a clear need for innovation in anti‐tuberculosis drug development. The zebrafish larva is an attractive disease model in tuberculosis research. To translate pharmacological findings to higher vertebrates, including humans, the internal exposure of drugs needs to be q...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: van Wijk, Rob C., Hu, Wanbin, Dijkema, Sharka M., van den Berg, Dirk‐Jan, Liu, Jeremy, Bahi, Rida, Verbeek, Fons J., Simonsson, Ulrika S.H., Spaink, Herman P., van der Graaf, Piet H., Krekels, Elke H.J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707096/
https://ncbi.nlm.nih.gov/pubmed/32860631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15247
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