Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

BACKGROUND AND PURPOSE: There is a clear need for innovation in anti‐tuberculosis drug development. The zebrafish larva is an attractive disease model in tuberculosis research. To translate pharmacological findings to higher vertebrates, including humans, the internal exposure of drugs needs to be q...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: van Wijk, Rob C., Hu, Wanbin, Dijkema, Sharka M., van den Berg, Dirk‐Jan, Liu, Jeremy, Bahi, Rida, Verbeek, Fons J., Simonsson, Ulrika S.H., Spaink, Herman P., van der Graaf, Piet H., Krekels, Elke H.J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707096/
https://ncbi.nlm.nih.gov/pubmed/32860631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15247
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